the severity factors are delineated by characteristics

Lorem ipsum dolor sit amet, consectetur adipiscing elit. The stability of results was assessed by conducting a sensitivity analysis which omitted each study in turn. Conclusion This study confirms race and ethnicity as predictors of severe COVID-19. Workers also have the right to refuse job if they believe in ________ faith that they are exposed to an imminent danger. Expert answered| capslock |Points 12946| Log in for more information. Coronavirus Disease 2019(COVID-19) which, was first identified in Wuhan, Hubei Province, China in December 2019, has already swept across the world. Bacterial Pneumonia Clinical Presentation - Medscape were observed in pediatric patients than elderly patients. 2 0 obj Fusce dui lectus, congue vel laoreet ac, dictum vitae odio. Pellentesque dapibus efficitur laoreet. In order to quantify the effects of risk factors on COVID-19 patients, we calculated population attributable fraction (PAF) by using the attributable fraction formula: Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. endstream endobj 209 0 obj <. https://doi.org/10.1371/journal.pone.0250602.s002, https://doi.org/10.1371/journal.pone.0250602.s003. The study population was 58% male and 42% female, with 36% of the total being children. which one Weegy: Cardiac output is the amount of blood pumped out with each heartbeat. Integrating deep learning CT-scan model, biological and clinical J. Autoimmun. and poor housekeeping can lead to all. 1 99]0Z2 w@ _T Besterfield emphasizes in this connection that no single list of . In terms of diabetes, this could compromise and weaken patients immune system thus worsening their conditions [75]. Ditches C. Asano, R., Rocha, A., Bastos, G. M., Electrical Transient Interaction Between Transformers and the Power System, CIGR A2-D1 Colloquium, Brugge, Belgium, October 2007. Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China. slipping. Clinical characteristics of COVID-19 complicated with pleural effusion 4. and poor housekeeping can lead to all of the following Laboratory abnormalities in children with mild and severe coronavirus disease 2019 (COVID-19): A pooled analysis and review. Chronic kidney disease; AKI, ReasonableB. and transmitted securely. We found that significantly higher frequencies of lymphadenopathy, skin rash, enlarged tonsils, etc. Factors Associated with Hospitalization and Disease Severity in a Donec aliquet. A. In this analysis, the ORs were used as approximations of RRs. We searched PubMed, Embase, Web of science and Cochrane Library for epidemiological studies of confirmed COVID-19, which include information about clinical characteristics and severity of patients disease. Based on the analysis of an increasing number of studies reporting details of BMI, we considered obesity as a risk factor. True OR False Best Answer Though we lacked sufficient evidence to support the results for these other complications except for shock, ARDS and AKI, the data we already had were of high consistency. Lorem ipsum dolor sit amet, consectetur adipiscing elit. 2020. One study shows that smoking can also enhance the expression of ACE2 [64] and this would raise the susceptibility. This site needs JavaScript to work properly. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). The comorbidities including hypertension, diabetes, CKD, coronary heart disease, COPD, cerebrovascular disease and chronic liver disease could probably aggravate the illness and this outcome was consistent with other studies. The impact of COVID-19 is due to both its rapid spread and its severity, but the determinants of severity have not been fully delineated. The severity factors are delineated by characteristics. The natural decrease in functional reserve brought about by the physiological aging process could reduce elders capability to resist infections like COVID-19. Slips, trips, and falls account for many general industry Two independent authors (LXY and ZXR) performed the data extraction by using standardized forms, which included date of publication, authors, region, number of included patients, sex, body mass index (BMI), smoking habits, comorbidities, complications, and severe or non-severe COVID-19. 7. The meta-regression analysis demonstrates that the association between coronary heart disease and increased severity was influenced by age (P = 0.013), and the discrepancy between patients median ages in eligible studies partly contributed to the heterogeneity. 8600 Rockville Pike Results: Forty-seven children met our study criteria. A. Zeng Z, Yu H, Chen H, Qi W, Chen L, Chen G, Yan W, Chen T, Ning Q, Han M, Wu D. Crit Care. Pellent, ia pulvinar tortor nec facilisis. An access gateB. Handrails or stair railsC. 12 inch wide treadsD.Toe boards. National Library of Medicine All rights reserved. True OR False 13. <> The severity factors are delineated by characteristics frequent, marginal, critical, and catastrophic. hbbd``b`:$gs q5A%@9HX~ & @BHr "&Fx Q'@ \+ Profits When conducting a five whys accident analysis the investigator will dig deeper to uncover an accident ____________. Crit. Catastrophic, critical, marginal, and negligible are used to differentiate the severity of a risk. Fever was the most common presentation (84.1%), but cough was present in only slightly over half of the patients. The authors have declared no competing interest. The details of the IRB/oversight body that provided approval or exemption for the research described are given below: University of Cincinnati Institutional Review Board. NOTE: Your email address is requested solely to identify you as the sender of this article. Click through the PLOS taxonomy to find articles in your field. Careers. Employee Injury C. Materials damage D. Mechanical Yes The characteristics of all the included studies are shown in Table 1. https://doi.org/10.1371/journal.pone.0250602.g001, https://doi.org/10.1371/journal.pone.0250602.t001. Discover a faster, simpler path to publishing in a high-quality journal. The severity factors are delineated by characteristics blank. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Though the degree varied, a large number of COVID-19 patients had hypoxaemia which may cause injury or apoptosis of cardiomyocytes [70]. We also found some comorbidities were potentially high-risk factors for severe disease and this is consistent with other recent studies [53, 55, 5759]. The cost of an accident is paid from company __________. Sex distribution of COVID-19 with different clinical classification. The impact of COVID-19 is due to both its rapid spread and its severity, but the determinants of severity have not been fully delineated. 8) and delineated on the map . Results Among the 689 COVID-19 patients included in our study, 29.2% were non-Hispanic White, 25.5% were non-Hispanic Black, 32.5% were Hispanic, and 12.8% were of Other race/ethnicity. Eosinopenia was a feature of higher levels of severity. More analyses need to be done in order to provide sufficient information and draw accurate conclusions about the controversial results above. HHS Vulnerability Disclosure, Help injuries. https://doi.org/10.1371/journal.pone.0250602.t004, We performed subgroup analyses to identify the possible sources of heterogeneity of some outcomes. Regosols, Cambisols and Vertisols were identified (Fig. Our analysis has shown that males, obese patients (BMI 30kg/m2), patients with advanced age or a smoking history faced a greater risk of having severe COVID-19. 5. Funnel plots were used to assess for publication bias and asymmetry was taken to indicate bias. For example, as a chronic respiratory illness, COPD has already led to airflow blockage and so raises the risk of respiratory complications like ARDS. In areas where mechanical equipment is used, narrow aisles No, Is the Subject Area "Cancer risk factors" applicable to this article? Factors Associated with Hospitalization and Disease Severity - medRxiv %%EOF (A-H) Forest plots of the association between (A) Chronic kidney disease, (B) Chronic obstructive pulmonary disease, (C) Coronary heart disease, (D) Malignancy, (E) Cerebrovascular disease, (F) Hypertension, (G) Diabetes, (H) Chronic liver disease and severe COVID-19 disease. OSHA has standards that cover: A. These steps are: 1. Severity A Likely B Occasional C Seldom D Unlikely E Catastrophic I EH EH H H M Critical II EH H H M L Marginal III H M M L L Negligible IV M L L L L EHExtremely High Risk HHigh Risk MModerate Risk LLow Risk RISK ASSESSMENT CODE CHART RISK ASSESSMENT CODE EXPLANATION Extremely High Risk Likely catastrophic loss The meta-analysis was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement [8]. broad scope, and wide readership a perfect fit for your research every time. the severity factors are delineated by characteristics One first approach to the concept of severity factor was made by Malewski et al. According to our analysis, ARDS, shock and AKI were the three major complications playing a role in severe conditions. The demographic characteristics including sex, age, smoking history and BMI were pooled for meta-analysis and the results are displayed in Fig 2. Median age of patients admitted to the registry was 27 years with an interquartile range of 8-47 years. 776 0 obj <>stream 13. 5. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Duration is the length of time the patient's signs and symptoms exist. seventh ed. Donec aliquet. In this study, the quality of evidence was higher since all the included studies were cohort studies rather than case-control studies, and we have included 41 eligible studies that were published from February,2020 to March, 2021, spanning a period of seven months. -, Du Y., Tu L., Zhu P., Mu M., Wang R., Yang P., Wang X., Hu C., Ping R., Hu P. Clinical features of 85 fatal cases of COVID-19 from wuhan: a retrospective observational study. Department of Epidemiology and Health Statistics, School of Health Sciences, Wuhan University, Wuhan, Hubei, China. The high level of ACE2 receptor expression in adipocytes may turn the adipose tissue into a viral carrier which could spread SARS-CoV-2 to other organs. No, Is the Subject Area "Metaanalysis" applicable to this article? In a binary logistic regression model, C-reactive protein level (OR 1.073, [CI, 1.013-1.136]; p = 0.017), CD8 T lymphocyte counts (OR 0.989, [CI, 0.979-1.000]; p = 0.043), and D-dimer (OR 5.313, [CI, 0.325-86.816]; p = 0.241) were independent predictors of disease severity.

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